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KMID : 0363220130510120983
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Korean Journal of Dermatology
2013 Volume.51 No. 12 p.983 ~ p.986
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Two Cases of Malignant Proliferating Trichilemmal Tumors: Large Tumors on the Scalp without Metastasis
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Seol Jung-Eun
Kim Hyo-Jin
Park In-Ho
Seo Jong-Keun
Sung Ho-Suk
Lee Sook-Kyung
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Abstract
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Proliferating trichilemmal tumor (PTT) is an uncommon neoplasm originated from the outer root sheath of a hairfollicle. Malignant transformation occurs occasionally in proliferating trichilemmal tumors, which can be manifestedby sudden rapid growths. Histologically, the malignant proliferating trichilemmal tumors (MPTTs) have shown severenuclear atypia, marked cellular pleomorphism with atypical mitoses, dyskeratotic cells and infiltrating margins.
Squamous cell carcinoma (SCC) should be differentiated with MPTT which indicates characteristic trichilemmalkeratinization. Large tumor is considered as a risk factor of metastasis in SCC, but the relationship between tumorsize and metastasis in the MPTT is not yet clarified. In this report, two patients have large erythematous noduleswith focal ulceration and necrosis on their scalps and were diagnosed as MPTT. Despite the large sizes of thetumors, there were no evidences of metastases. Herein, we report 2 cases of the large MPTT which are presentedwithout metastasis.
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KEYWORD
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Malignant proliferating trichilemmal tumor, Metastasis, Squamous cell carcinoma
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